Andrey Popatanasov | Neurobiology | Best Researcher Award

Dr. Andrey Popatanasov | Neurobiology | Best Researcher Award

Researcher, Institute of Neuro biology, Bulgarian Academy of Sciences, Bulgaria

Andrey Popatanasov is a Research Assistant at the Institute of Neurobiology, Bulgarian Academy of Sciences. With a unique multidisciplinary background, he holds BSc degrees in Psychology, Physics, and Biology, with MSc degrees in Clinical Psychology, Medical Physics, and Molecular Biology. He is completing his PhD in Human and Animal Physiology, demonstrating a lifelong commitment to scientific learning. Since 2016, Andrey has played a key role in neurobiological research, particularly on neurodegenerative disorders. His work involves molecular docking, in silico and in vivo studies, and the interaction of quantum radiation with living tissues. He has authored over a dozen peer‑reviewed articles and contributed to book chapters, demonstrating strong publication productivity. As a member of Bulgarian scientific societies in physiology, toxicology, and peptides, he actively engages in professional development and scholarly communication. His interdisciplinary expertise spans neuroscience, biophysics, psychology, and molecular biology, aligning theory with practical therapeutics and public health applications.

Professional Profile

Education

Andrey Popatanasov completed a diverse academic foundation demonstrating deep integration across fields. He earned BSc degrees in Psychology, Physics, and Biology, offering a broad base in both social science and natural science domains. He then advanced to MSc qualifications in Clinical Psychology, Medical Physics, and Molecular Biology, refining clinical, physical, and cellular expertise. Currently, he is finalizing his PhD in Human and Animal Physiology at the Bulgarian Academy of Sciences, integrating his multidisciplinary knowledge into experimental design and physiological interpretation. His academic versatility supports exploration at molecular, psychological, and systemic levels—ideal for neurobiological research. Andrey’s academic journey has provided advanced training in psychophysiology, radiobiology, molecular modeling, and ethology. This cross-disciplinary education empowers him to bridge computational, experimental, and clinical worlds, optimizing both research breadth and depth, and preparing him for leadership in translational neurobiology.

Experience

Since 2016, Andrey has served as a Research Assistant at the Institute of Neurobiology (Bulgarian Academy of Sciences), where he contributes to neurodegenerative and affective‑behavioral studies. In 2015, he worked briefly as a Molecular Biologist at the Institute of Molecular Biology “Roumen Tsanev.” He taught physics at Sofia University’s Faculty of Physics (2014–2015) and performed specialized physics research at the Institute of Optical Materials and Technologies (2012). Earlier, between 2002 and 2005, he was a Psychophysiology researcher at the Institute of Psychology, Bulgarian Academy of Sciences—focusing on cognitive‑developmental studies in children. Across these roles, Andrey developed skills in experimental design, laboratory methods, in silico modeling, data analysis, and interdisciplinary collaboration. His diverse work experience reflects adaptability, integrative thinking, and proficiency across biological, physical, and psychological science—well-suited for modern neurobiology settings.

Research Focus

Andrey’s research intersects neuroscience, psychology, molecular biology, and biophysics. He investigates affective and pro-social behaviors in neurological and psychiatric conditions, including developing and testing novel ligands and neuroactive compounds in rodent disease models such as Parkinson’s and Alzheimer’s. His projects span in silico molecular docking, in vivo neuropharmacology, and mechanistic studies of ligand–biomolecule interactions. He also investigates the effects of electromagnetic radiation from quantum generators on biological soft tissue, bridging theoretical optics and experimental biology. Genomic complexity and control of expression during the cell cycle have been explored in laboratory and computational settings. He further examines language complexity’s impact on brain development in disabled children. Current work includes evaluating new memantine-based derivatives against Alzheimer’s pathology, with a focus on translational potential. Andrey’s research emphasizes integrative, multidisciplinary methods aimed at understanding neurological disorders and developing next-generation therapies.

Publication Top Notes

  1. In Silico and In Vivo Evaluation of N-Sinapoyl‑memantine as a Candidate for Alzheimer’s Disease Management (Crystals, May 2025).
    Summary: First author; used computational docking and mouse models to test memantine derivative for neuroprotection.

  2. Mutation Breeding Research in Sweet Pepper (Book chapter, 2023; in Mutation Breeding for Sustainable Food Production, ISBN 978‑981‑16‑9720‑3).
    Summary: Examines mutation breeding strategies for climate-resilient agriculture.

  3. Effect of Castalagin Against HSV‑1 Infection in Newborn Mice (Natural Product Research, Dec 2023).
    Summary: Evaluated antiviral effects of castalagin in neonatal HSV‑1 mouse model.

  4. Neuroprotective Effect of 2‑Methylcinnamic Acid Amide in an MPTP‑Induced Parkinson’s Model (Crystals, Oct 2022).
    Summary: Demonstrated in vivo efficacy and docking-based binding analysis for a novel compound.

  5. Tyrosinyl‑amantadine in Parkinson’s Disease Rats (Journal of Molecular Neuroscience, Apr 2022).
    Summary: Reported behavioral and molecular improvements in 6‑OHDA Parkinsonian rats.

  6. Safety and Activity of Newly Synthesized Amantadine Derivative (Farmacia, Dec 2021).
    Summary: Preclinical toxicity and pharmacological profiling for amantadine analogue.

  7. Canopy Effects on Ophrys insectifera Distribution (Journal of BioScience and Biotechnology, 2020).
    Summary: Used imaging to study habitat effects on endangered orchid.

  8. New Neurotensin Analogue for Affective Symptoms in Parkinson’s Rats (Bulgarian Chemical Communications, 2020).
    Summary: Behavioral efficacy of a neurotensin analogue in disease model.

  9. Ellagic Acid Prevents Cognitive Decline in Alzheimer’s Mice (Bulgarian Chemical Communications, 2018).
    Summary: Mechanistic insights into ellagic acid’s neuroprotection in AD mouse model.

  10. Preventive Effect of Neurotensin Analogues in Parkinson’s Rats (Journal of Molecular Neuroscience, Dec 2018).
    Summary: Demonstrated neurotensin analogues’ protective roles against dopaminergic degeneration.

Conclusion

Andrey Popatanasov exemplifies the profile of a committed, interdisciplinary researcher with contributions spanning fundamental and applied neuroscience, molecular medicine, and psychology. His work displays both depth and societal relevance, particularly in managing neurodegenerative and cognitive disorders. Despite modest citation metrics and limited industrial engagement, his diverse academic training, integrative research approach, and scholarly productivity make him a worthy contender for the Best Researcher Award.

Stuart Maudsley | Receptor Pharmacology | Best Researcher Award

Prof. Dr. Stuart Maudsley | Receptor Pharmacology | Best Researcher Award

Senior Fellow/Professor, H. Lee Moffitt Cancer Center, United States

Dr. Stuart Russell Maudsley is a renowned pharmacologist with a distinguished career in receptor biology, specializing in therapeutic precision medicines targeting GPCRs (G-Protein Coupled Receptors). He is currently the Principal Investigator at the Maudsley Lab and a Senior Member at Moffitt Cancer Center. Dr. Maudsley is also a co-founder of HeptOME, focusing on aging-related diseases and metabolic dysfunction. With over two decades of research experience, he has held prominent roles including scientific advisor to the Belgian Superior Health Council, and various leadership roles at Johns Hopkins, the NIH, and VIB. His groundbreaking work includes receptor pharmacology and molecular biology studies aimed at advancing novel treatments for complex human disorders, particularly cancer and neurodegenerative diseases. His career has been recognized globally, earning numerous awards and honors for his contributions to molecular pharmacology.

Profile

Education

Dr. Stuart Russell Maudsley obtained his PhD in Pharmacology from the University of Leeds, UK, where he was awarded the Ackroyd, Brotherton & Brown Scholarship. His doctoral research focused on electrophysiological and molecular biological studies of Tachykinin receptors, marking the beginning of his illustrious career in receptor pharmacology. Prior to his PhD, Dr. Maudsley earned a First-Class B.Sc. in Pharmacology from the same institution. During his academic tenure, he engaged in advanced studies of ion channel electrophysiology and the pharmacology of the central nervous system, topics that have significantly shaped his subsequent research endeavors. His educational foundation laid the groundwork for his future contributions in both academia and the pharmaceutical industry, particularly in the development of novel therapeutic strategies for neurodegenerative diseases, cancer, and metabolic disorders.

Experience

Dr. Stuart Russell Maudsley boasts an extensive career with leadership roles across academia, industry, and government. He is the Principal Investigator at the Maudsley Lab at Moffitt Cancer Center and the co-founder of HeptOME, where he focuses on receptor-targeted therapies for aging-related metabolic diseases. Throughout his career, Dr. Maudsley has held various significant positions, including Adjunct Director at VIB, Vice-Chair at the University of Antwerp’s Department of Biomedical Science, and Principal Investigator at the NIH. He has contributed to numerous international projects, including his work as a Special Science Advisor to the Belgian Superior Health Council. Dr. Maudsley has also led scientific teams at Johnson & Johnson, the U.S. Department of Defense, and the NIH, where he made crucial contributions to drug development and the understanding of receptor pharmacology. His leadership and expertise have resulted in groundbreaking advancements in the pharmacology and therapeutics of complex diseases.

Awards and Honors

Dr. Stuart Russell Maudsley has received numerous prestigious awards and honors throughout his career. Notable recognitions include the 2021 UAntwerpen Seal of Excellence Grant, 2020 Johnson & Johnson Research Grant, and the 2019 FWO Doctoral Research Grant. He has also been honored with the FWO Senior Research Fellows Grant and the UAntwerpen-IOF Industrial Collaboration Research Grant in 2019. His work in molecular pharmacology and receptor biology has led to the receipt of multiple awards from both European and American institutions, including the National Institutes of Health On-the-Spot Award (2011-2013). Dr. Maudsley’s groundbreaking research on neurodegenerative diseases, aging, and metabolic dysfunction has earned him widespread recognition in the scientific community. His scientific excellence and contributions to pharmacology, drug discovery, and biotechnology continue to inspire advancements in the treatment of complex human disorders.

Research Focus

Dr. Stuart Russell Maudsley’s research primarily focuses on receptor pharmacology, with a special emphasis on G-Protein Coupled Receptors (GPCRs) and their role in human disease. His work seeks to identify and develop precision GPCR-targeted therapies for cancer, neurodegenerative disorders, and metabolic diseases such as obesity and aging-related conditions. Through his leadership in both academic labs and the biotech industry, Dr. Maudsley investigates novel biotechnological platforms, including both wet and dry biomedical technologies. He aims to create multidimensional precision medicines that can more effectively treat complex disorders, particularly those related to aging. His current research in the Maudsley Lab centers on the molecular mechanisms that underlie aging and neurodegenerative diseases, as well as the identification of potential therapeutic agents. By exploring the intricate signaling pathways of GPCRs, Dr. Maudsley is paving the way for the development of innovative treatments for diseases that currently lack effective therapies.

Publications Top Notes

  • β-Arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes – Science (1999) 🧬📚
  • BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders – Trends in Neurosciences (2004) 🧠
  • The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women – International Journal of Obesity (2011) 🍏🏃‍♀️
  • Gonadotropin-releasing hormone receptors – Endocrine Reviews (2004) 💊🔬
  • Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma – Free Radical Biology and Medicine (2007) 🏥
  • Caloric restriction and intermittent fasting: two potential diets for successful brain aging – Ageing Research Reviews (2006) 🧠
  • The β2-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor – Journal of Biological Chemistry (2000) 🧬🔬