Dr. Liudmila Alexandrova | Biology and Life Sciences | Research Excellence Award
EIMB RAS | Russia
Liudmila A. Alexandrova is a senior researcher at the Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, with a distinguished career spanning several decades in molecular biology and medicinal chemistry. She received her education from Lomonosov Moscow State University and completed her postgraduate training at EIMB RAS. An Alexander von Humboldt Foundation, she has gained extensive international research experience through postdoctoral work in Czechoslovakia and Germany. Her scientific contributions include the design and synthesis of biologically active modified nucleosides and nucleotides, with a strong focus on antiviral, antibacterial, and antifungal drug mechanisms. She has authored more than 100 peer-reviewed publications and holds five Russian patents, reflecting a substantial body of documented research output. She has successfully supervised four PhD dissertations and over 35 diploma theses, while currently mentoring postgraduate researchers. Recipient of two Russian Academy of Sciences awards, her work has significantly advanced the development of novel bacterial and fungal growth inhibitors, establishing her as a respected contributor to biomedical and chemical research with lasting scientific influence.
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Featured Publications
The synthesis and antituberculosis activity of 5′-nor carbocyclic uracil derivatives
E. Matyugina, A. Khandazhinskaya, L. Chernousova, S. Andreevskaya, Bioorganic & Medicinal Chemistry, 20(22), 6680–6686, 2012. (Citations: 82)
Inhibition of Mycobacterium tuberculosis strains H37Rv and MDR MS-115 by a new set of C5 modified pyrimidine nucleosides
E.R. Shmalenyuk, L.N. Chernousova, I.L. Karpenko, S.N. Kochetkov, Bioorganic & Medicinal Chemistry, 21(17), 4874–4884, 2013. (Citations: 72)
2′-Deoxynucleoside 5′-triphosphates modified at α-, β- and γ-phosphates as substrates for DNA polymerases
L.A. Alexandrova, A.Y. Skoblov, M.V. Jasko, L.S. Victorova, A.A. Krayevsky, Nucleic Acids Research, 26(3), 778–786, 1998. (Citations: 68)
Oligonucleotide derivatives bearing reactive and stabilizing groups attached to C5 of deoxyuridine
A.S. Levina, D.R. Tabatadse, L.M. Khalimskaya, T.A. Prichodko, G.V. Shishkin, Bioconjugate Chemistry, 4(5), 319–325, 1993. (Citations: 49)
Colorimetric solid-phase minisequencing assay illustrated by detection of alpha 1-antitrypsin Z mutation
L. Harju, T. Weber, L. Alexandrova, M. Lukin, M. Ranki, A. Jalanko, Clinical Chemistry, 39(11), 2282–2287, 1993. (Citations: 47)