Eyachew Misganew Tegaw | Cancer | Best Researcher Award

Assist. Prof. Dr. Eyachew Misganew Tegaw | Cancer | Best Researcher Award

Assistant Professor of Medical Physics, Debre Tabor University, Ethiopia

Dr. Eyachew Misganew Tegaw is an Assistant Professor at Debre Tabor University, Ethiopia, specializing in Medical Physics. He earned his PhD from Tehran University of Medical Sciences, focusing on enhancing intraoperative radiotherapy for breast cancer using nanoparticles. With a robust background in condensed matter and applied physics, Dr. Tegaw has contributed significantly to radiotherapy, dosimetry, and medical imaging research. His work integrates advanced computational methods, including Monte Carlo simulations and machine learning, to improve cancer treatment outcomes. Dr. Tegaw’s dedication to academia and research has positioned him as a leading figure in medical physics, with numerous publications and collaborations that underscore his commitment to advancing cancer therapy.

Professional Profile

Education

Dr. Eyachew Misganew Tegaw’s academic journey began with a BSc in Applied Physics from the University of Gondar, Ethiopia. He then pursued an MSc in Condensed Matter Physics at Mekelle University, where he conducted a theoretical study on gold-coated iron nanoparticles for medical applications. His academic pursuits culminated in a PhD in Medical Physics from Tehran University of Medical Sciences, Iran. His doctoral research focused on enhancing intraoperative radiotherapy for breast cancer using effective nanoparticles, under the guidance of esteemed supervisors and advisors. Throughout his education, Dr. Tegaw has undertaken comprehensive coursework in areas such as radiobiology, radiation protection, imaging techniques, and computational physics, laying a strong foundation for his research endeavors in medical physics.

Experience 

Dr. Eyachew Misganew Tegaw has amassed extensive experience in academia and research. He began his career as a Lecturer in the Department of Physics at Debre Tabor University, Ethiopia, where he served from April 2011 to August 2016. Following his doctoral studies, he resumed his role at the university as an Assistant Professor in October 2020. In addition to teaching, Dr. Tegaw has held leadership positions, including Head of the Physics Department and Chairman of the Ethiopian Space Science Society’s Debre Tabor branch. His responsibilities have encompassed curriculum development, research supervision, and organizing workshops aimed at enhancing educational quality and research output. Dr. Tegaw’s commitment to education and research has significantly contributed to the advancement of medical physics in Ethiopia.

Research Focus 

Dr. Eyachew Misganew Tegaw’s research centers on advancing cancer treatment through medical physics. His primary focus areas include radiotherapy techniques such as 3D-CRT, IMRT, VMAT, and IORT, with a particular interest in dose enhancement using nanoparticles. He employs Monte Carlo simulations to model radiation interactions and optimize treatment planning. Dr. Tegaw also explores the integration of artificial intelligence and machine learning to predict treatment outcomes and personalize therapy. His interdisciplinary approach extends to imaging modalities like CT, MRI, and nuclear medicine, aiming to improve diagnostic accuracy and treatment efficacy. Through his research, Dr. Tegaw seeks to bridge the gap between theoretical physics and clinical applications, contributing to the development of more effective and safer cancer therapies.

Publication Top Notes

  1. Explainable Machine Learning to Compare the Overall Survival Status Between Patients Receiving Mastectomy and Breast Conserving Surgeries

    • Authors: Betelhem Bizuneh Asfaw, Eyachew Misganew Tegaw

    • Published: March 2025

    • Journal: Scientific Reports

    • Summary: This study utilizes explainable machine learning techniques to compare survival outcomes between breast cancer patients undergoing mastectomy versus breast-conserving surgery, providing insights into treatment efficacy.

  2. Explainable Machine Learning and Feature Interpretation to Predict Survival Outcomes in the Treatment of Lung Cancer

    • Authors: Eyachew Misganew Tegaw, Betelhem Bizuneh Asfaw

    • Published: May 2025

    • Journal: Seminars in Oncology

    • Summary: The research applies explainable machine learning models to predict survival outcomes in lung cancer treatment, highlighting key biomarkers influencing patient prognosis.

  3. Attenuation Correction for Dedicated Cardiac SPECT Imaging Without Using Transmission Data

    • Authors: Getu Tadesse, Parham Geramifar, Mehrshad Abbasi, Eyachew Misganew Tegaw, et al.

    • Published: February 2023

    • Journal: Molecular Imaging and Radionuclide Therapy

    • Summary: This study proposes a method for attenuation correction in cardiac SPECT imaging without relying on transmission data, enhancing image quality and diagnostic accuracy.

  4. Diagnostic Performance of Mammography and Ultrasound in Breast Cancer: A Systematic Review and Meta-Analysis

    • Authors: Getu Tadesse, Eyachew Misganew Tegaw, Ejigu Kebede Abdisa

    • Published: January 2023

    • Journal: Journal of Ultrasound

    • Summary: The meta-analysis evaluates the diagnostic accuracy of mammography and ultrasound in breast cancer detection, providing evidence-based recommendations for clinical practice.

  5. Gold-Nanoparticle-Enriched Breast Tissue in Breast Cancer Treatment Using the INTRABEAM® System: A Monte Carlo Study

    • Authors: Eyachew Misganew Tegaw, Ghazale Geraily, Somayeh Gholami, Mehdi Shojaei, Getu Tadesse

    • Published: March 2022

    • Journal: Radiation and Environmental Biophysics

    • Summary: This research investigates the use of gold nanoparticles to enhance the efficacy of intraoperative radiotherapy in breast cancer treatment, utilizing Monte Carlo simulations for dose distribution analysis.

  6. Comparison of Organs at Risk Doses Between Deep Inspiration Breath-Hold and Free-Breathing Techniques During Radiotherapy of Left-Sided Breast Cancer: A Meta-Analysis

    • Authors: Eyachew Misganew Tegaw, Getu Tadesse, Ghazale Geraily, Somayeh Gholami, Wondesen Tassew Gebreamlak

    • Published: March 2022

    • Journal: Polish Journal of Medical Physics and Engineering

    • Summary: The study compares radiation doses to critical organs using deep inspiration breath-hold versus free-breathing techniques in left-sided breast cancer radiotherapy, highlighting the benefits of breath-hold methods.

  7. Dosimetric Effect of Nanoparticles in the Breast Cancer Treatment Using INTRABEAM® System with Spherical Applicators in the Presence of Tissue Heterogeneities: A Monte Carlo Study

    • Authors: Eyachew Misganew Tegaw, Ghazale Geraily, Seyed Mohsen Etesami, Hossein Ghanbari, Somayeh Gholami, Mehdi Shojaei, Mostafa Farzin, Getu Tadesse

    • Published: April 2021

    • Journal: Biomedical Physics & Engineering Express

    • Summary: This study evaluates the impact of tissue heterogeneities on dose distribution when using nanoparticles in intraoperative radiotherapy for breast cancer, employing Monte Carlo simulations for analysis.

  8. A Comparison Between EGSnrc/Epp and MCNP Monte Carlo Codes in Simulation of the INTRABEAM® System with Spherical Applicators

    • Authors: Eyachew Misganew Tegaw, Ghazale Geraily, Seyed Mohsen Etesami, Somayeh Gholami, Hossein Ghanbari, Mostafa Farzin, Getu Tadesse, Mehdi Shojaei

    • Published: January 2021

    • Journal: Journal of Biomedical Physics & Engineering

    • Summary: The research compares two Monte Carlo simulation codes, EGSnrc/Epp and MCNP, in modeling the INTRABEAM® system for breast cancer treatment, assessing their accuracy and computational efficiency.

Conclusion

Dr. Eyachew Misganew Tegaw stands out as a promising and innovative researcher in the field of medical physics and oncology technology. His diverse yet focused expertise, combined with his growing publication record, interdisciplinary approaches, and contribution to science leadership in Ethiopia, strongly support his nomination for a Best Researcher Award.

Ismail Kara | Cancer Genetic | Best Faculty Award

Prof. Dr. Ismail Kara | Cancer Genetic | Best Faculty Award

Cukurova university faculty of medicine department of medical oncology, Turkey

Prof. Dr. İsmail Oğuz Kara is a distinguished medical oncologist serving at Çukurova University Faculty of Medicine. He completed his medical degree at Hacettepe University in 1995 and earned specialization in Internal Medicine and Medical Oncology from Çukurova University. With a career spanning over two decades, Dr. Kara has held several academic titles from Assistant Professor to Full Professor since 2013. His expertise lies in clinical oncology, translational cancer research, and leading clinical trials. He has served as a principal or co-investigator in numerous international and national clinical studies, particularly in melanoma, gastric, and hepatocellular carcinomas. Dr. Kara holds extensive certifications in Good Clinical Practice (GCP) and remains active in the Turkish Oncology Group. He has published impactful articles in prestigious journals and is committed to advancing evidence-based cancer therapies. His work continues to shape cancer treatment protocols and research across Turkey and beyond.

Professional Profile

Education

Prof. Dr. İsmail Oğuz Kara’s academic journey began at Hacettepe University Faculty of Medicine, where he obtained his Medical Doctorate in 1995. Following his graduation, he pursued a Specialization in Internal Medicine at Çukurova University Faculty of Medicine, completing it in 2002. He continued with subspecialty training in Medical Oncology and earned the title of Yandal Uzmanı (subspecialist) in 2005. In the same institution, he began his academic career as an Assistant Professor in 2006, promoted to Associate Professor in 2007, and finally became a Full Professor in April 2013. His educational trajectory reflects a robust focus on oncology, reinforced by continuous professional development through certified international trainings, including multiple ICH-GCP certifications. These qualifications have positioned him as an expert in both academic and clinical aspects of oncology, with a deep understanding of patient care, clinical trial management, and research-based education.

Experience

Prof. Dr. İsmail Kara has dedicated his career to clinical medicine and oncology research at Çukurova University Faculty of Medicine. From 1996 to 2002, he served as a Research Assistant, followed by a Subspecialty Research Role until 2005. He became a Specialist Doctor in 2005, quickly advancing to Assistant Professor (2006–2007), then Associate Professor (2007–2013), and ultimately a Full Professor in 2013. Throughout his tenure, he has been instrumental in pioneering and leading clinical oncology practices and supervising numerous clinical trials as a Principal Investigator. Dr. Kara’s experience is enriched by collaborations with global pharmaceutical entities such as Pfizer, Bayer, MSD, and BMS, facilitating high-impact research on cancer therapies. His career reflects a synergy of clinical excellence, academic leadership, and research advancement, making him a key contributor to the field of medical oncology in Turkey.

Research Focus

Prof. Dr. İsmail Oğuz Kara’s research primarily focuses on clinical and translational oncology, particularly in melanoma, gastric cancer, hepatocellular carcinoma, and lung cancer. He is deeply involved in multicenter clinical trials examining second-line treatment efficacies, immunotherapy outcomes, and predictive biomarkers. He has investigated CEA/Albumin and CRP/Albumin ratios as novel prognostic tools in gastric cancer and led numerous GCP-certified clinical studies. His current work contributes significantly to identifying molecular predictors of treatment response and survival outcomes, aimed at personalizing oncology therapy. As part of the Turkish Oncology Group, he continuously collaborates with national and international experts, contributing to evidence-based practice guidelines. His future-oriented research aims to integrate cancer genetics and precision medicine into routine oncological care to enhance survival rates and quality of life for cancer patients.

Publication Top Notes

1.
📘 Title: Prognostic factors and outcomes of adjuvant and first-line metastatic treatments in melanoma: A Turkish Oncology Group study
👨‍⚕️ Authors: Majidova N., Arak H., Özalp F.R., Özgün A., Kostek O., Kara İ.O., et al.
📚 Journal: Scientific Reports
📅 Year: 2025
🔗 Summary: This study evaluated survival and prognostic variables in patients with melanoma receiving adjuvant and metastatic treatments. It emphasizes the clinical importance of baseline characteristics and genetic markers in improving melanoma management.

2.
📘 Title: Efficacy of Second-Line Treatments After Atezolizumab and Bevacizumab in Advanced Hepatocellular Carcinoma and Related Prognostic Factors
👨‍⚕️ Authors: Majidova N., Yaslikaya S.S., Mıldanoglu M.M., Yalçın S., Kostek O., Kara İ.O., et al.
📚 Journal: Turkish Journal of Gastroenterology
📅 Year: 2025
🔗 Summary: This multicenter research assessed outcomes of second-line therapies in hepatocellular carcinoma following Atezolizumab-Bevacizumab failure. It identified key prognostic variables affecting progression and survival.

3.
📘 Title: Can the Pathological Response in Patients with Locally Advanced Gastric Cancer Receiving Neoadjuvant Treatment Be Predicted by the CEA/Albumin and CRP/Albumin Ratios?
👨‍⚕️ Authors: Bayram E., Kidi M.M., Camadan Y.A., Kara I.Ö., Şahin B.S.
📚 Journal: Journal of Clinical Medicine
📅 Year: 2024
🔗 Summary: Investigates inflammatory and tumor marker-based ratios as predictive tools for neoadjuvant treatment response in gastric cancer, providing a potential non-invasive diagnostic method.

Conclusion

Prof. Dr. İsmail Oğuz Kara is highly suitable for the Research for Best Faculty Award based on his deep academic foundation, long-standing and active involvement in clinical trials, and recent peer-reviewed publications. His commitment to oncology research, particularly in Turkey, positions him as a significant contributor to the field. With slight improvements in international visibility and citation metrics, his impact could become even more far-reaching.

 

Davide Frumento | Molecular Oncology | Best Researcher Award

Prof. Davide Frumento | Molecular Oncology | Best Researcher Award

Adjunct Professor, RomaTre University, Italy

Dr. Davide Frumento is an experienced academic and researcher currently serving as an adjunct professor at Roma Tre University and Milan University in Italy. With a strong background in chemical engineering and biotechnology, he has contributed extensively to the scientific community in various research fields. His multidisciplinary expertise bridges molecular oncology, epigenetics, and biotechnology. Passionate about advancing scientific knowledge, Dr. Frumento has worked in both academic and industry settings, collaborating with top-tier institutions like Harvard University. His research is focused on innovative solutions in health, biotechnology, and environmental sustainability.

Profile

Orcid

Education 

Dr. Davide Frumento holds a PhD in Chemical Engineering from Genoa University (2012-2015), where he specialized in biotechnology applications. He graduated with a BSc and MSc in Biotechnology from the same institution (2005-2011). He further broadened his qualifications with a certification as a Scientific Expert for Criminal Procedures Court of Savona (2024). His academic journey reflects a consistent commitment to advancing his knowledge and skills, particularly in molecular sciences. Throughout his career, Dr. Frumento has continuously expanded his expertise by engaging in postdoctoral research at prominent institutions, including the University of Genoa, Milan University, and Harvard University. His extensive education has laid a strong foundation for his contributions to both academia and the industry.

Experience

Dr. Frumento has a distinguished career in academia and research. Since February 2025, he has served as an adjunct professor at the Penitentiary University Center, Milan University. He also holds a position as an adjunct professor in Epigenetics at Roma Tre University, Italy, since 2021. Previously, he has worked as a postdoctoral researcher at Genoa University, San Raffaele Hospital, and Milan University, where he contributed to research in health sciences and biotechnology. His postdoctoral research has spanned multiple departments, including DISSAL, DIMES, and DIFAR, focusing on various aspects of molecular biology, microbiota, and immunology. Dr. Frumento’s industrial experience includes a role as a Quality Control Microbiology Analyst at Noberasco SpA, further showcasing his diverse professional background. His broad expertise in both academic and industry research makes him a significant contributor to the scientific community.

Awards and Honors

Dr. Frumento’s contributions to the scientific field have earned him several prestigious awards. Notably, in 2021, he received the Smart Cup Scientific Award for Innovation and Technology from Regione Liguria, recognizing his work in health and environmental technology implementation. Earlier, in 2014, he won the Start Cup Scientific Award from the University of Genoa for his innovative work on a microtubular photobioreactor, aimed at improving microalgae culture for commercial use. His dedication to scientific innovation is also reflected in his membership in multiple scientific and technical organizations, including STRA and the Research Data Alliance. Dr. Frumento’s recognition within both the academic and industry sectors highlights his commitment to advancing research in molecular sciences, biotechnology, and environmental sustainability.

Research Focus

Dr. Frumento’s research spans several cutting-edge areas of molecular biology, with particular emphasis on biotechnology, molecular oncology, epigenetics, and environmental sciences. His work on the human microbiota’s role in immune responses and diseases such as hepatitis C and multiple sclerosis has contributed significantly to understanding their interplay. Additionally, he has explored the role of sirtuins in autoimmunity, studying SIRT6 inhibition as a therapeutic strategy for multiple sclerosis and other autoimmune diseases. Dr. Frumento’s research in the application of light-based technologies in immunotherapy further highlights his focus on innovative solutions for health and disease management. His work extends to environmental sustainability, where he investigates biotechnological applications for waste management and bioengineering, particularly in areas such as microalgae culture. By blending molecular biology with practical applications in medicine and the environment, Dr. Frumento continues to push the boundaries of scientific discovery.

Publication Top Notes

  • Interaction Between Human Microbiota, Immune System, and Hepatitis C Virus Infection: A Narrative Review 🦠
  • Light-based technologies in immunotherapy: advances, mechanisms, and applications 💡
  • Effects of Wildfire Exposure on the Human Immune System 🔥🧬
  • Small Molecule Tyrosine Kinase Inhibitors (TKIs) for Glioblastoma Treatment 💊
  • Health Technology Assessment (HTA) sull’introduzione di coorti aggiuntive per la vaccinazione contro il meningococco 🦠💉
  • Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration 🧠
  • E-Muser (Enhanced Multiple Sclerosis Expected Rate): A Technical Improvement 🧑‍🔬
  • Sarcoglycanopathies: A Novel Predictive Approach 🧬
  • SIRT6 inhibition as a therapeutic approach for treating multiple sclerosis 🧠💉
  • DAI (Disease Aggressiveness Index) Implementation 📊
  • MuSER (Multiple Sclerosis Expected Rate) Predictive Model Development 🧠📈
  • Gut Microbiota Role in Liver Regeneration 🦠💡
  • Microbiota and HCV Infection Interplay 🦠
  • Oral bacteria contribution in wine flavor perception 🍷🦠
  • The efficacy of the new anti HCV therapy, implementation of a path based on the logic of micro-elimination in the Department of Mental Health and Addictions ASL4 Chiavarese 💊