Federal University of Rio de Janeiro | Brazil
Patricia Dias Fernandes is a distinguished Full Professor at the Federal University of Rio de Janeiro, Brazil, recognized for her pioneering contributions to pharmacology and inflammation research. she has established herself as a leading figure in experimental pharmacology. Her academic background and research career focus on preclinical models of chronic inflammatory diseases, including Crohn’s disease, endometriosis, cancer, and SARS-CoV-2-induced pneumonia. She leads several multidisciplinary projects exploring novel diagnostic markers and therapeutic agents through integrative biochemical and omics approaches. Prof. Fernandes has registered multiple patents on innovative antiviral compounds, highlighting her translational impact from laboratory to clinical relevance. As an Associate Editor of the Journal of Ethnopharmacology, she actively promotes scientific excellence and innovation in drug discovery. Her collaborations with prominent researchers worldwide, including Pierre Sirois, Fabio Boylan, and Claudio Viegas, strengthen her global scientific network. Recipient of numerous national and institutional recognitions, Prof. Fernandes continues to advance the field of pharmacology by searching for new bioactive and synthetic compounds to treat chronic inflammatory diseases, shaping the next generation of therapeutic strategies.
Featured Publications
Franco, G. D. R. R., Gontijo, V. S., Viegas, F. P. D., Silva, M. D. F., Ortiz, C. J. C., Damásio, C. M., Silva, I. M. F., Campos, T. G., Reis, E. V. S., Clarindo, F. A., et al. (2025). Novel multifunctional cannabidiol-based analogues with in silico, in vitro, and in vivo anti-SARS-CoV-2 effect. Pharmaceuticals, 18(10), 1565.
Moraes, R. S. M., Botelho, A. B. M., Pinto, G. T. A., Rodrigues, S. C., Martins, M. T. M., Soares, D. L. A., Cruz, C. C., Pinto, A. D. A., Dias, F. R. F., Fernandes, P. D., et al. (2025). Chemistry, applications, and synthesis methods of indole derivatives: A comprehensive review. The Chemical Record. Advance online publication.
Guerra, F. S., Freitas, R. H. C. N., Moldovan, F., Rocha, D. R. D., Carvalho, R. S., & Fernandes, P. D. (2025). Design, synthesis, and bioactivity assessment of modified vemurafenib analog. Pharmaceuticals, 18(8), 1161.
de Souza, M. L., de Paiva, J. P. B., Franco, G. D. R. R., Gontijo, V. S., Alves, M. A., de Souza, H. M. R., Lontra, A. C. P., de Oliveira, E. A., Giorno, T. B. S., Guedes, I. A., et al. (2025). Design, synthesis, and evaluation of antinociceptive properties of novel CBD-based terpene-cinnamoyl-acyl-hydrazone analogues. Pharmaceuticals, 18(5), 755.
França, P. R. C., de Paiva, J. P. B., de Carvalho, R. R., Figueiredo, C. P., Sirois, P., & Fernandes, P. D. (2024). R-954, a bradykinin B1 receptor antagonist, as a potential therapy in a preclinical endometriosis model. Peptides, 171, 171294.