Donglin Ren | Medical Application | Best Researcher Award

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Prof. Dr Donglin Ren | Medical Application | Best Researcher Award

Professor, The Sixth Affiliated Hospital, Sun Yat-sen University, China

Professor Dong-Lin Ren is a renowned expert in colorectal surgery, specializing in the integration of Traditional Chinese Medicine (TCM) and Western Medicine for anorectal and pelvic floor disorders. He holds multiple esteemed positions, including Chief Consultant at the Department of Colorectal Surgery at the Sixth Affiliated Hospital of Sun Yat-sen University. As a professor at Sun Yat-sen University and a mentor to doctoral and postdoctoral candidates, he has made significant contributions to both clinical practice and medical education. With over 250 peer-reviewed publications and more than 20 patents, his work spans innovative surgical techniques, minimally invasive treatments for colorectal tumors, and reconstructive surgeries. Professor Ren’s leadership in professional societies and his pioneering work in complex anorectal disease management have earned him national recognition as a leading medical talent. His dedication to advancing healthcare makes him a key figure in both the medical and academic communities.

Profile

Scopus

Strengths for the Award

  1. Extensive Academic and Research Contributions:
    • Publications: Professor Ren has published over 250 peer-reviewed articles, including over 50 in high-impact SCI journals. His work contributes significantly to the fields of colorectal surgery, anorectal diseases, and the integration of Traditional Chinese Medicine with Western Medicine.
    • Research Leadership: He has led or participated in more than 10 national or provincial research projects, showcasing his leadership and dedication to advancing medical research.
    • Innovative Patents: Professor Ren holds over 20 national invention and utility model patents, underlining his commitment to creating new solutions in the medical field.
  2. Clinical Expertise:
    • His clinical work on complex colorectal and anal diseases, including advanced techniques like NOSES for low rectal cancer and minimally invasive treatments for anorectal disorders, has set new standards in the field. This directly influences his research on treatment outcomes and surgical innovations.
  3. Multidisciplinary Approach:
    • Professor Ren’s integration of Traditional Chinese Medicine (TCM) and Western Medicine is a unique approach that enriches his research perspective. This not only brings innovation but also opens up new research avenues in integrative medicine.
  4. Teaching and Mentorship:
    • As a professor and doctoral/postdoctoral supervisor, his impact on the next generation of researchers is substantial. His role in educating and mentoring budding medical professionals enhances the depth and longevity of his contributions to the medical field.
  5. Recognition and Influence:
    • Professor Ren has received notable awards, including the title of Leading Medical Talent in Guangdong Province and China’s National Famous Doctor award. These recognitions underscore his esteemed position within the medical community.
    • His leadership roles in major professional societies and committees further establish him as a key figure in shaping the future of colorectal and pelvic floor surgery.

Areas for Improvement

  1. Broader International Visibility:
    • While Professor Ren is highly influential within China, his international visibility could be expanded. Greater engagement in global collaborations and international research networks would amplify the global impact of his work.
  2. Public Outreach of Research Findings:
    • Although Professor Ren has published numerous articles, more efforts could be made to translate his findings into practical guidelines for healthcare professionals globally. This would help to disseminate his innovative approaches to a broader audience.
  3. Focus on Translational Research:
    • While his work is highly clinical, more focus on the translational aspects (such as moving research from the bench to bedside more rapidly) could make his contributions even more impactful.

Education

Professor Dong-Lin Ren earned his medical degree from Sun Yat-sen University, where he further advanced his studies, eventually becoming a Professor of Surgery at the institution. His academic journey is marked by a deep commitment to integrating Traditional Chinese Medicine with Western surgical techniques. Throughout his education, Professor Ren specialized in colorectal surgery, gaining extensive clinical experience in proctology, pelvic floor disorders, and colorectal oncology. He trained under esteemed mentors in both Western and Chinese medicine fields, giving him a unique perspective on patient care. His postdoctoral work focused on minimally invasive procedures for colorectal cancer and complex anal diseases. Additionally, Professor Ren has trained and mentored numerous doctoral and postdoctoral candidates in surgical research, integrating his knowledge of both Eastern and Western medicine. His continuous pursuit of higher education and research excellence has positioned him as a leading figure in his field, influencing medical practices globally.

Experience

Professor Dong-Lin Ren has an extensive career in both clinical practice and academia. He is the Chief Consultant and Director at the Department of Colorectal Surgery, Department of Integrated Traditional Chinese and Western Medicine for Anorectal Surgery, and Pelvic Floor Center at the Sixth Affiliated Hospital of Sun Yat-sen University. In addition to his clinical expertise, he served as Vice President and Operation Director at the hospital, and is the Dean of the School of Pelvic Floor Anorectal Surgery. His experience spans advanced surgical procedures, including minimally invasive treatments for colorectal cancer and the integration of Traditional Chinese Medicine (TCM) with Western approaches. Professor Ren also leads a team performing the largest number of anorectal procedures in China, specializing in managing complex conditions like recurrent anal fistulas and rectal prolapse. He has guided and mentored numerous doctors, shaping the future of colorectal surgery both domestically and internationally.

Awards and Honors

Professor Dong-Lin Ren has received numerous prestigious awards and honors throughout his career. He is recognized as a Leading Medical Talent in Guangdong Province and was the third recipient of China’s National Famous Doctors award, a testament to his excellence in both clinical practice and medical research. His contributions to the field of colorectal surgery have earned him leadership roles in various professional societies. Professor Ren is the Chairman of the Asia Alliance of Colorectal and Pelvic Floor Disorders and holds significant positions in other medical organizations, such as the China Geriatric Health Care Association and the Chinese Preventive Medicine Association. He is also honored with several honorary chairman and vice chairman roles in prominent Chinese medical committees. His work has been pivotal in advancing colorectal and pelvic floor medicine, and these recognitions affirm his status as a leading figure in the field.

Research Focus

Professor Dong-Lin Ren’s research focuses on the integration of Traditional Chinese Medicine (TCM) and Western Medicine to develop innovative treatments for colorectal and anorectal diseases. He specializes in the minimally invasive treatment of low rectal cancer, using anus-preserving technologies and NOSES techniques to avoid abdominal and pelvic incisions. His research includes complex conditions like anal fistulas, chronic constipation, rectovaginal fistulas, and recurrent rectal cancer. He has led or participated in multiple national research projects, contributing to the development of MRI-based deep learning classifiers and other diagnostic tools. Additionally, his work on single-cell RNA sequencing and the effects of astragaloside IV in colorectal cancer treatment has made significant advancements in understanding cellular dynamics and therapeutic interventions. Professor Ren’s research efforts aim to improve both patient outcomes and the effectiveness of surgical and non-surgical treatments in colorectal diseases.

Publication Top Notes

  1. “Development and validation of the MRI-based deep learning classifier for distinguishing perianal fistulizing Crohn’s disease from cryptoglandular fistula: a multicenter cohort study” 🧠📚
  2. “Single-cell transcriptome analysis reveals immunosuppressive landscape in overweight and obese colorectal cancer” 🧬⚖️
  3. “Single-cell RNA sequencing reveals cellular dynamics and therapeutic effects of astragaloside IV in slow transit constipation” 🧬💊
  4. “Evaluation of transrectal ultrasound-guided tru-cut biopsy as a complementary method for predicting pathological complete response in rectal cancer after neoadjuvant treatment” 🔬📈
  5. “Stapled transperineal rectovaginal fistula repair for low- and mid-level rectovaginal fistulas: A comparison study with rectal mucosal advancement flap repair” 🔪🩺
  6. “Preoperative assessment of fistula-in-ano using SonoVue enhancement during three-dimensional transperineal ultrasound” 🔬📸
  7. “A magnetic resonance imaging-based decision-making tool for predicting complex anal fistulas healing in the early postoperative period” 🧠💡
  8. “Cancer-associated fibroblasts undergoing neoadjuvant chemotherapy suppress rectal cancer revealed by single-cell and spatial transcriptomics” 🧬💔
  9. “Unraveling dynamic interactions between tumor-associated macrophages and consensus molecular subtypes in colorectal cancer: An integrative analysis of single-cell and bulk RNA transcriptome” 🔬🦠
  10. “Should the diverting enterostomy for refractory anorectal Crohn’s disease be considered in advance?” 💡🌱

Conclusion

Professor Dong-Lin Ren is a highly suitable candidate for the Best Researcher Award. His contributions to both clinical practice and research are substantial and have led to groundbreaking advancements in colorectal and anorectal surgery. His leadership in integrating Traditional Chinese Medicine with Western practices provides a unique and innovative approach that benefits both patient care and medical research. With his continued impact on the medical community through teaching, research, and clinical excellence, Professor Ren’s work is deserving of recognition on an international level. Expanding his global research network and increasing public outreach could further solidify his standing as a leader in medical research.

 

 

Jorge Amador Berlanga-Acosta | Medicine and Health Sciences | Best Researcher Award

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Prof Dr Jorge Amador Berlanga-Acosta | Medicine and Health Sciences | Best Researcher Award

Research project leader, Center for Genetic Engineering and Biotechnology, Cuba

Dr. Jorge Amador Berlanga Acosta is a distinguished Cuban veterinary medicine and pharmaceutical scientist, born on October 11, 1962, in Bayamo, Granma, Cuba. With a career spanning over three decades, he specializes in the pharmacological applications of Epidermal Growth Factor (EGF) for wound healing and diabetic foot ulcers. He holds several prestigious titles, including Member of Honor of the Cuban National Academy of Science and Distinguished Professor at the University of Electronic Science and Technology of China. Dr. Berlanga has made significant contributions to biomedical research and has been instrumental in various clinical trials and technical missions across multiple continents, earning recognition for his impactful work in regenerative medicine and pharmacology. His expertise is complemented by a strong commitment to education and mentorship in the scientific community. 🌟

Profile

Google Scholar

Strengths for the Award

  1. Extensive Education and Training: Dr. Berlanga has a solid academic background with a Doctor of Veterinary Medicine and a Ph.D. in Pharmaceutical Sciences and Pharmacology. His post-doctoral fellowships at prestigious institutions like the University of Alberta and Imperial Cancer Research Fund highlight his commitment to advancing medical knowledge.
  2. Research Contributions: His extensive work on epidermal growth factor (EGF) and its applications in wound healing, particularly in diabetic foot ulcers, is groundbreaking. He has led numerous research projects and has a substantial number of publications in reputable journals, indicating his active engagement in critical biomedical research.
  3. Recognition and Awards: Dr. Berlanga has received numerous prestigious awards, including the “Héroe del Trabajo de la República de Cuba” and various international recognitions, showcasing his impact and contributions to the field.
  4. Leadership in Scientific Community: His roles in coordinating research commissions, leading projects, and serving as a speaker at over 40 international conferences illustrate his leadership and influence in the scientific community.
  5. Multidisciplinary Approach: His research spans various aspects of pharmacology, tissue repair, and regenerative medicine, demonstrating his ability to integrate knowledge across disciplines effectively.
  6. International Collaboration: Dr. Berlanga’s involvement in international workshops and conferences shows his commitment to collaboration and the dissemination of knowledge globally.

Areas for Improvement

  1. Broader Research Scope: While Dr. Berlanga’s focus on EGF is significant, exploring additional areas of research could enhance his impact. Diversifying his research portfolio may lead to novel insights and applications in other fields of medicine.
  2. Public Engagement and Communication: Increasing his outreach efforts to communicate research findings to the general public could enhance the visibility of his work and its implications for healthcare.
  3. Mentorship Opportunities: Engaging more with younger researchers and students through mentorship programs could foster the next generation of scientists and broaden the research community’s perspectives.
  4. Interdisciplinary Collaboration: Further collaboration with other scientific disciplines, such as engineering or technology, could lead to innovative approaches in his research areas.

Education

Dr. Berlanga’s educational journey began with primary education in Bayamo, Granma, followed by secondary schooling. He obtained his Doctor of Veterinary Medicine from the Universidad de Granma in 1985. He furthered his studies with a PhD in Pharmaceutical Sciences and Pharmacology from the Universidad de La Habana in 2000. His academic pursuits included post-doctoral fellowships at renowned institutions, such as the University of Alberta in Canada and the Leicester General Hospital in the UK, focusing on wound healing and gastroenterology. Additionally, he completed numerous specialization courses in clinical pathology, molecular biology, and experimental pharmacology. His diverse educational background has equipped him with the knowledge and skills to advance biomedical research and contribute to the field significantly. 🎓

Experience

Dr. Berlanga’s professional experience includes roles as an instructor and assistant lecturer in Anatomical Pathology at the Universidad de Granma and as an Associate Professor of Pathology. He has been a researcher at the Centro de Ingeniería Genética y Biotecnología (CIGB) in Havana, focusing on EGF’s pharmacological effects and wound healing mechanisms. Over the years, he has led various departments and projects within CIGB, including preclinical studies and diabetic foot ulcer healing initiatives. His leadership has driven significant advancements in understanding tissue repair and regeneration. In addition to his research, Dr. Berlanga has been a prominent speaker at numerous international conferences, sharing his findings and fostering collaboration in the scientific community. His extensive experience has established him as a leading figure in the field of biomedical sciences. 🔬

Awards and Honors

Dr. Berlanga’s contributions to science have earned him numerous accolades. He received the Alberta Heritage Foundation Scholarship in 1995 and the Royal Society Annual Award in 1998. In 2011, he was honored with the Distinción Carlos J. Finlay and recognized by the World Intellectual Property Organization as the best young inventor. His achievements include being named Hijo Ilustre de Granma and Bayamo, as well as receiving the prestigious title of Héroe del Trabajo de la República de Cuba in 2020. He has also been acknowledged as a Distinguished Professor at the University of Electronic Science and Technology of China. These awards highlight his significant impact on science and society through innovative research and dedication to education. 🏆

Research Focus

Dr. Berlanga’s research primarily focuses on the pharmacological applications of Epidermal Growth Factor (EGF) in wound healing and tissue regeneration. His investigations have led to the development of various animal models to study EGF’s effects on diabetic foot ulcers, ischemia/reperfusion injury, and gastrointestinal health. He explores the molecular mechanisms underlying EGF’s protective properties and its role in enhancing healing processes. His work also includes studying cellular pathologic memory and its implications in diabetes and wound chronicity. Dr. Berlanga’s commitment to advancing regenerative medicine continues to shape therapeutic strategies for complex wound healing challenges, making significant contributions to biomedical science. 🧬

Publication Top Notes

  • Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis
  • The pro‐inflammatory environment in recalcitrant diabetic foot wounds
  • Intra‐lesional injections of recombinant human epidermal growth factor promote granulation and healing in advanced diabetic foot ulcers: multicenter, randomised, placebo …
  • Epidermal growth factor in clinical practice–a review of its biological actions, clinical indications and safety implications
  • Intralesional administration of epidermal growth factor‐based formulation (Heberprot‐P) in chronic diabetic foot ulcer: treatment up to complete wound closure
  • Intralesional injections of Citoprot‐P® (recombinant human epidermal growth factor) in advanced diabetic foot ulcers with risk of amputation
  • Glucose toxic effects on granulation tissue productive cells: the diabetics’ impaired healing
  • Epidermal growth factor intralesional infiltrations can prevent amputation in patients with advanced diabetic foot wounds
  • Diabetic foot ulcers and epidermal growth factor: revisiting the local delivery route for a successful outcome
  • Gastrointestinal cell proliferation and crypt fission are separate but complementary means of increasing tissue mass following infusion of epidermal growth factor in rats
  • Diabetic lower extremity wounds: the rationale for growth factors‐based infiltration treatment
  • Healing enhancement of diabetic wounds by locally infiltrated epidermal growth factor is associated with systemic oxidative stress reduction
  • Cellular senescence as the pathogenic hub of diabetes-related wound chronicity
  • Wound chronicity, impaired immunity and infection in diabetic patients
  • Insulin resistance at the crossroad of Alzheimer disease pathology: A review
  • Potency and stability of C terminal truncated human epidermal growth factor
  • Systemic translation of locally infiltrated epidermal growth factor in diabetic lower extremity wounds
  • Epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) as tissue healing agents: clarifying concerns about their possible role in malignant transformation and …
  • Intestinal growth in parenterally‐fed rats induced by the combined effects of glucagon‐like peptide 2 and epidermal growth factor
  • Medical practice confirms clinical trial results of the use of intralesional human recombinant epidermal growth factor in advanced diabetic foot ulcers

Conclusion

Dr. Jorge Amador Berlanga Acosta exemplifies the qualities of an outstanding researcher through his extensive educational background, significant contributions to science, and recognized leadership. His innovative work on EGF and wound healing positions him as a strong candidate for the Best Researcher Award. By broadening his research scope, enhancing public engagement, and fostering mentorship, he can further elevate his impact on the scientific community and society at large.