Alejandra Guillermina Miranda-Díaz | Clinical Research | Women Researcher Award

Prof. Dr. Alejandra Guillermina Miranda-Díaz | Clinical Research | Women Researcher Award

Alejandra Guillermina Miranda Díaz is a distinguished Professor and Researcher with extensive experience in the fields of general surgery, pharmacology, and clinical research. Having pursued a lifelong passion for surgery, she became a Medical Surgeon and Partero at the University of Guadalajara, later specializing in General Surgery and obtaining a Master’s in Medical Sciences and a Doctorate in Pharmacology. Her academic journey reflects a commitment to advancing medical research, particularly in inflammatory diseases and oxidative stress. Miranda Díaz has held significant roles in academia, such as coordinating master’s programs in Medical Sciences and mentoring numerous graduate students. Her expertise has led to collaborations with hospitals and medical professionals on various groundbreaking studies. Her research focuses on understanding the mechanisms of inflammation and oxidative stress, contributing significantly to advancements in clinical pharmacology and surgical practice.

Profile

Education 

Alejandra Guillermina Miranda Díaz’s educational background is rich and diverse, rooted in the University of Guadalajara. She began her academic journey with a Bachelor’s degree in Medicine (1971–1977), followed by an advanced specialization in General Surgery (1983). Driven by a deep interest in medical research, she pursued a Master’s in Medical Sciences (1992), and later, a Doctorate in Pharmacology (2003), solidifying her status as an expert in the field. These academic milestones, supported by a strong foundation in clinical surgery, enabled her to bridge the gap between practical medical procedures and theoretical scientific exploration. Throughout her career, she has been dedicated to applying her educational experience to improve medical knowledge, train future professionals, and contribute to groundbreaking research in fields such as inflammation, oxidative stress, and pharmacology.

Experience 

Alejandra Guillermina Miranda Díaz has dedicated over 40 years to both clinical practice and academic instruction. She began her career as a General Surgeon in the IMSS (Mexican Social Security Institute) in 1983, advancing through various leadership roles such as the Coordinator of the Laparoscopic Surgery Program and Sub-Director of the Medical Morning Shift at Hospital General Regional No. 45. In 2001, she transitioned to academia, becoming a Professor and Researcher in the Department of Physiology at the University of Guadalajara’s Center for Health Sciences. Her role as the Coordinator for various Master’s and Doctorate programs in Medical Sciences allowed her to shape the careers of numerous students. Her expertise has earned her a prominent place in the field, with notable distinctions such as membership in multiple medical associations and the System of National Researchers (SNI), where she holds the level II status until 2026.

Research Focus 

Alejandra Guillermina Miranda Díaz’s research primarily focuses on the role of inflammation and oxidative stress in various diseases, particularly in nephrology and metabolic disorders. Her research examines the complex mechanisms of these processes in conditions such as lupus nephritis, diabetes, and obesity. By studying toll-like receptors (TLRs) such as TLR7 and TLR9, Miranda Díaz explores how these receptors influence disease progression and contribute to inflammatory responses. Her work is pivotal in understanding the broader implications of oxidative stress and inflammation, offering potential therapeutic targets for chronic diseases. Currently, her research includes investigating how inflammation and oxidative stress affect renal function in lupus nephritis and exploring their potential links to metabolic syndrome and obesity. Her work fosters collaboration between medical institutions and researchers, aiming to improve patient care and medical treatment strategies through evidence-based scientific discoveries.

Publication Top Notes

  • The Role of TLRs in Obesity and Its Related Metabolic Disorders 🧬
  • The Expression of Toll-like Receptors (TLR7 and TLR9) in Class III and Class IV of Recently Diagnosed Lupus Nephritis with 12-Month Follow-Up 🧪
  • The Sigma-1 Receptor Exacerbates Cardiac Dysfunction Induced by Obstructive Nephropathy: A Role for Sexual Dimorphism 💖
  • Clinical Impact Using Low Dose Mycophenolate Mofetil with Tacrolimus on Acute Rejection, Infectious Diseases, and Non-Infectious Complications in Renal Transplant: A Single Hospital Experience in Mexico 🏥
  • The Effect of Enalapril, Losartan, or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients 🌱
  • Foods with Potential Prooxidant and Antioxidant Effects Involved in Parkinson’s Disease 🧠
  • The Role of Oxidative Stress in Physiopathology and Pharmacological Treatment with Pro- and Antioxidant Properties in Chronic Diseases ⚖️
  • The Effect of Visceral Abdominal Fat Volume on Oxidative Stress and Proinflammatory Cytokines in Subjects with Normal Weight, Overweight, and Obesity 🏃‍♀️