Prof. Suresh Kumar Thallapuranam | Biochemistry | Best Researcher Award

Prof. Suresh Kumar Thallapuranam | Biochemistry | Best Researcher Award

Mildred Cooper Chair of Biochemistry & Bioinformatics, University of AArkansas, United States

Prof. Suresh Kumar Thallapuranam is a distinguished academic and researcher in the field of biochemistry and bioinformatics. Born on February 2, 1961, he obtained his Ph.D. from Osmania University, Hyderabad, India, in 1993. Prof. Thallapuranam’s career spans multiple international institutions, including the Center for Cellular & Molecular Biology in India, National Tsing Hua University in Taiwan, and the University of Arkansas. His research contributions in protein folding, bioactive peptides, and structural bioinformatics have earned him recognition in the scientific community. He is currently a professor and holds the Mildred B. Cooper Endowed Chair of Bioinformatics at the University of Arkansas. His work focuses on understanding molecular mechanisms and protein interactions with various applications in health and disease.

Profile

Education

Prof. Suresh Kumar Thallapuranam completed his undergraduate and postgraduate studies in India before pursuing a Ph.D. in Biochemistry at Osmania University, Hyderabad, in 1993. His doctoral research laid the foundation for his expertise in molecular biology and structural bioinformatics. After completing his Ph.D., he embarked on an international academic journey, serving as a research scientist at the Center for Cellular & Molecular Biology in Hyderabad from 1991-1994. His postdoctoral work at National Tsing Hua University in Taiwan solidified his interest in protein folding, molecular interactions, and structural biology. Prof. Thallapuranam’s academic achievements continued at the University of Arkansas, where he has grown his career from a research assistant professor to a full professor. His research contributions and teaching excellence have made him a prominent figure in both the academic and scientific communities.

Experience

Prof. Suresh Kumar Thallapuranam has a rich and varied academic career that spans over three decades. From 1991 to 1994, he served as a research scientist at the Center for Cellular & Molecular Biology in India, focusing on molecular biology and protein studies. In 1994, he moved to Taiwan, where he worked as a research associate and later as a staff scientist at National Tsing Hua University until 2003. In 2003, he joined the University of Arkansas as a research assistant professor and progressively advanced through academic ranks. He has been an assistant professor (2006-2010), an associate professor (2010-2015), and since 2015, a full professor. Prof. Thallapuranam is also the Director of the Office of Undergraduate Research at the University of Arkansas since 2020. His research interests cover protein structure, folding, and bioinformatics, with significant contributions to understanding the molecular mechanisms in various health-related proteins.

Awards and Honors

Prof. Suresh Kumar Thallapuranam has received numerous awards and recognitions for his outstanding contributions to research and teaching. His excellence in mentoring and teaching was acknowledged through the Honors College Outstanding Mentor Award from 2007 to 2023. He received the Robert C. and Sandra Connor Fellowship in 2008 for outstanding research and teaching, and in 2010, he was honored with the Faculty Gold Medal from the Chancellor’s Office for his exceptional work with undergraduates. In 2015, he was inducted into the University of Arkansas Teaching Academy. Prof. Thallapuranam has been recognized by the National Academy of Inventors in 2017 and received the Charles Nadine Baum University of Arkansas Distinguished Award for Outstanding Teaching in 2018. Other prestigious awards include the Master Teacher Award (2014), Collis Geren Outstanding Interdisciplinary Faculty Award (2020), and the Nolan Faculty Award for outstanding teaching, research, and service in 2023.

Research Focus

Prof. Suresh Kumar Thallapuranam’s research focuses on understanding the molecular mechanisms governing protein folding, interactions, and bioinformatics. His work spans a range of topics, from non-classical secretion of proteins like Interleukin 1α and Fibroblast Growth Factors (FGFs) to investigating the role of cation-pi interactions in protein stability. He is particularly interested in the structure-function relationships of bioactive peptides and the molecular basis of FGF-induced craniosynostosis. Prof. Thallapuranam’s research also delves into the design of drugs targeting FGF-induced pathogenesis and other health-related protein interactions. He collaborates with multiple researchers in various disciplines, including chemistry, biological sciences, and biomedical engineering. Additionally, Prof. Thallapuranam is dedicated to advancing NMR techniques for studying membrane proteins and structural dynamics in complex cellular environments. His interdisciplinary approach connects basic research with potential clinical applications in cancer, viral infections, and tissue regeneration.

Publication Top Notes

  • Polyphenol-induced protein structural modifications in sorghum on pasting properties 🧬📖 (2024)
  • Elucidating the effect of polyphenol-protein interactions on rheological properties of purple waxy rice 🌾🧪 (2024)
  • Molecular Modelling, Synthesis, and In-Vitro Assay to Identify Potential Antiviral Peptides Targeting the 3-Chymotrypsin-Like Protease of SARS-CoV-2 🦠💊 (2023)
  • A meta-analysis of the protein components in rattlesnake venom 🐍🔬 (2021)
  • Silver ions caused faster diffusive dynamics of histone-like nucleoid-structuring proteins in live bacteria ⚡🦠 (2020)
  • Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity 💉⚙️ (2019)
  • Stilbenoid prenyltransferases define key steps in the diversification of peanut phytoalexins 🌰🔬 (2018)
  • Physicochemical Properties and ACE-I Inhibitory Activity of Protein Hydrolysates from a Non-Genetically Modified Soy Cultivar 🌱⚡ (2016)

NARESH BABU CHILAMAKURU | Molecular Biology | Best Researcher Award

Dr NARESH BABU CHILAMAKURU | Molecular Biology | Best Researcher Award

Assistant Professor, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) – Autonomous, India

Dr. C. Naresh Babu, M. Pharm., Ph.D., is an accomplished academician and researcher with expertise in medicinal chemistry, pharmaceutical sciences, and drug discovery. Currently an Assistant Professor at Raghavendra Institute of Pharmaceutical Education & Research (RIPER) in Ananthapuramu, India, Dr. Naresh Babu has contributed significantly to the field of pharmacy through research in drug development, molecular docking, and QSAR studies. His work focuses on synthesizing novel compounds for treating tuberculosis and other diseases. With over a decade of teaching experience, he is also recognized for his leadership in coordinating research and quality assurance at RIPER. He has published numerous research papers in esteemed journals and holds various professional memberships.

Profile

Google Scholar

Strengths for the Award

Dr. C. Naresh Babu demonstrates numerous qualities and accomplishments that make him a highly suitable candidate for the Best Researcher Award. Some of his key strengths include:

  1. Extensive Academic and Research Experience:
    • Dr. Babu holds a M. Pharm degree and is pursuing advanced research with a Ph.D., showcasing his strong academic background and deep understanding of pharmaceutical sciences.
    • His role as a Junior Research Fellow in a DST-SERB-funded project underscores his involvement in cutting-edge research.
    • As an Assistant Professor at Raghavendra Institute of Pharmaceutical Education & Research (RIPER), he has made significant contributions to the academic development of future professionals in pharmaceutical sciences, teaching a wide array of subjects.
  2. Research Publications and Contributions:
    • Dr. Babu has an impressive publication record, with multiple research articles published in reputed journals such as Future Journal of Pharmaceutical Sciences, Brazilian Journal of Pharmaceutical Sciences, and Indian Journal of Heterocyclic Chemistry, among others.
    • His research has notably focused on drug discovery, tuberculosis, and antimicrobial agents, which are highly relevant areas in current global health concerns.
    • He has contributed to novel compounds and drug discovery, including research on multidrug-resistant tuberculosis and antitubercular agents, which have high potential for impact in the pharmaceutical industry.
  3. Innovative Research Projects:
    • Dr. Babu’s work on 4-oxoazetidin derivatives and their potential to treat multidrug-resistant tuberculosis is groundbreaking, demonstrating his ability to address pressing health issues with innovative solutions.
    • He is involved in in-silico drug design, molecular docking, QSAR studies, and predicting drug toxicity—advanced methodologies that enhance the efficiency and efficacy of drug discovery.
  4. Collaboration and Networking:
    • His collaborative work with other professionals and academic institutions reflects his ability to work as part of a team and engage in multidisciplinary research.
    • His memberships in prestigious organizations such as the Indian Pharmaceutical Association (IPA) and the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) further illustrate his strong professional network.
  5. Awards and Recognitions:
    • Dr. Babu has received the Best Young Teacher Award from the IPA in 2016, highlighting his dedication to both teaching and research.
    • His consistent academic excellence is demonstrated by his 1st rank in the B. Pharm academic exams in 2006-2008, and his successful qualification in GPAT 2010.

Areas for Improvement 

While Dr. Babu’s profile is very impressive, some areas for further development could include:

  1. Broader International Collaboration:
    • While Dr. Babu’s work is highly valued within national and regional contexts, increasing international research collaborations could further elevate his global research impact.
    • Engaging in international research conferences or working on multi-country research initiatives could enhance visibility and bring exposure to new ideas, techniques, and methodologies.
  2. Research Funding and Leadership:
    • Although he has successfully worked as a Junior Research Fellow in a government-funded project, seeking opportunities to lead or initiate larger-scale projects with funding from international bodies could further strengthen his research profile.
    • Developing leadership roles in collaborative projects could allow Dr. Babu to have a more prominent influence in the global pharmaceutical research community.
  3. Translational Research:
    • Dr. Babu’s research is predominantly focused on drug discovery at a basic research level, which is crucial. However, translating these findings into clinical trials or industry applications could greatly enhance the practical impact of his work. Collaboration with industry partners or clinical researchers could facilitate this transition.
  4. Diversity in Research Topics:
    • While his work on tuberculosis and antimicrobial resistance is vital, expanding into other disease areas or therapeutic approaches (such as cancer, cardiovascular diseases, or neurodegenerative disorders) could increase the scope and impact of his research.

Education

Dr. Naresh Babu completed his Master of Pharmacy (M.Ph) from Sri Padmavathi School of Pharmacy, Tiruchanoor, under JNT University, Anantapur with an impressive 80.37%. He holds a Bachelor of Pharmacy (B.Ph) from A.K. College of Pharmacy, KrishnanKoil, and a Diploma in Pharmacy (D.Ph) from S.V. Govt. Polytechnic, Tirupati. His academic journey also includes Intermediate and Secondary School Certificate from Sri Vidya Darsini Junior College and Mittamalleswara High School, respectively. He further enhanced his research capabilities with a Ph.D. in Pharmaceutical Sciences, focusing on drug development and molecular pharmacology.

Experience

Dr. Naresh Babu has over 12 years of experience in pharmaceutical education and research. He currently serves as an Assistant Professor at RIPER, where he teaches subjects such as Medicinal Chemistry, Pharmaceutical Analysis, and Quality Assurance. Previously, he was a Junior Research Fellow in the DST-SERB funded project, where he focused on drug discovery and testing. Additionally, he has worked as a faculty member at RIPER since 2012, contributing to the academic growth of pharmacy students. Dr. Naresh also has hands-on experience as a pharmacist and intern, having worked in various pharmaceutical settings, including Med Plus Pharmacy and a government hospital in Pulivendla.

Awards and Honors

  • Best Young Teacher Award (2016), recognized by the Executive Council of IPA, Ananthapuramu.
  • Qualified GPAT (2010) with All India Rank 1933.
  • Gold Medal for securing 1st Rank in academic exams in B.Pharm (2006-2008).
  • Recognized for outstanding contributions to research and education, including leadership roles such as Coordinator of Research & Development (R&D) Cell and IQAC at RIPER.
  • Life Member of multiple professional organizations including the Indian Pharmaceutical Association (IPA) and International Society for Pharmacoeconomics and Outcomes Research (ISPOR).

Research Focus

Dr. Naresh Babu’s research primarily focuses on drug discovery and the development of novel therapeutic agents. He specializes in synthesizing organic molecules, biological evaluation, and computational methods like QSAR and docking studies. His work addresses the growing challenge of drug-resistant tuberculosis by designing compounds targeting Mycobacterium tuberculosis. Additionally, Dr. Naresh is involved in antimicrobial and anticancer drug development, along with studies on the pharmacokinetic properties of new drug candidates. His multidisciplinary approach integrates synthetic chemistry, biochemistry, and pharmacology to identify innovative solutions for current medical needs.

Publications

  1. Antitubercular Drugs and 4-Oxoazetidin derivatives combination for the treatment of Multidrug-Resistant Tuberculosis 🦠💊
  2. In vitro Antitubercular and Antibacterial activities of isolated constituents and column fractions from Cassia occidentalis, Camellia sinensis, and Ananas comosus 🌿🔬
  3. Insights on recent approaches in drug discovery strategies and untapped drug targets against drug resistance 📚🔍
  4. SYNTHESIS, CHARACTERISATION AND ANTI-TUBERCULAR ACTIVITY OF SOME NEW 3,5-DISUBSTITUTED-2,4-THIAZOLIDINEDIONES 🧪🔥
  5. Spatial Long-Term Memory Retention by Banana and Papaya Peel Extract: In silico and in vivo Evaluation 🍌🍍🧠
  6. Method Development and Validation of Dual Wavelength UV Spectrophotometric Method for Paracetamol and Caffeine 📑💡
  7. Preclinical evaluation of nephroprotective potential of a probiotic formulation LOBUN on Cyclosporine-A induced renal dysfunction 🧬💊
  8. Apoptosis-Mediated Cytotoxic Effect of Caralluma adscendens var. attenuata on Colon and Hepatic Cancer Cell Lines 🍃⚖️
  9. Myoinositol and methyl stearate increases rifampicin susceptibility among drug‐resistant Mycobacterium tuberculosis 🧪💥
  10. Novel stilbene scaffolds efficiently target Mycobacterium tuberculosis nucleoid-associated protein, HU 🦠🔬

Conclusion

Dr. C. Naresh Babu is highly deserving of the Best Researcher Award due to his innovative research contributions, dedication to teaching, and impressive publication record. His work in pharmaceutical sciences, especially in areas related to drug discovery for tuberculosis and antimicrobial resistance, is not only academically significant but also of immense practical importance. By continuing to expand his international collaborations and taking on leadership roles in larger research projects, Dr. Babu could further enhance his global recognition. His ongoing commitment to high-quality research and development makes him a valuable asset to the academic and scientific communities.