Associate professor, doctoral supervisor, Shandong Normal University, China
Dr. Wang Hui is an Associate Professor and doctoral supervisor at Shandong Normal University, specializing in molecular fluorescence probes for real-time in vivo imaging. Her research focuses on developing probes for detecting reactive oxygen species (ROS) and proteins in live organisms, aiming to enhance early diagnosis and understanding of diseases such as atherosclerosis, rheumatoid arthritis, and idiopathic pulmonary fibrosis. Dr. Wang has authored over 30 peer-reviewed articles in high-impact journals like Angewandte Chemie International Edition and Analytical Chemistry. She has also filed multiple patents related to her probe technologies. Her work has been recognized by the National Natural Science Foundation of China and the Shandong Provincial Natural Science Foundation. Dr. Wang is a member of the Chinese Chemical Society and collaborates with the Institute of Oceanology, Chinese Academy of Sciences, on projects related to marine pollution.
Profile
Orcid
Education
Dr. Wang Hui completed her undergraduate studies in Physics at Shandong Normal University from 2013 to 2017. She then pursued a Ph.D. in Chemistry at Nankai University, graduating in 2022. Her doctoral research focused on the development of molecular fluorescence probes for bioimaging applications. Throughout her academic journey, Dr. Wang has been involved in various research projects, including those funded by the National Natural Science Foundation of China and the Shandong Provincial Natural Science Foundation. Her educational background has provided her with a strong foundation in both theoretical and practical aspects of molecular chemistry and bioimaging techniques.
Experience
Dr. Wang Hui has extensive experience in the field of molecular fluorescence probes and bioimaging. Since joining Shandong Normal University, she has led several research projects aimed at developing innovative probes for detecting ROS and proteins in live organisms. Her work has led to the creation of novel probes such as the C-HBrO-GGT and GolgiROS, which have been instrumental in studying diseases like atherosclerosis and hypertension. Dr. Wang has also been involved in collaborations with institutions like the Institute of Oceanology, Chinese Academy of Sciences, focusing on environmental applications of fluorescence probes. Her contributions have been recognized through numerous publications in high-impact journals and several patents.
Research Focus
Dr. Wang Hui’s research focuses on the development of molecular fluorescence probes for specific imaging of biomolecules. By combining these probes with fluorescence imaging technology, her work aims to achieve early warning and diagnosis of major diseases such as atherosclerosis, rheumatoid arthritis, and idiopathic pulmonary fibrosis. Her innovative approaches include the development of dual-mode fluorescent probes and two-photon fluorescence imaging techniques to detect bioactive molecules like ROS and proteins in the lesion sites of live mice. These advancements have the potential to significantly enhance early disease diagnosis and drug discovery, providing fundamental tools for real-time organelle-level redox research.
Publication Top Notes
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“Prediction of Early Atherosclerotic Plaques Using a Sequence‐Activated Fluorescence Probe for the Simultaneous Detection of γ‐Glutamyl Transpeptidase and Hypobromous Acid”
Angewandte Chemie International Edition, 2023, 136(1): e202315861
Developed a dual-activated probe for early detection of atherosclerotic plaques.
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“Fluorescence Probes for Sensing and Imaging within Golgi Apparatus”
Coordination Chemistry Reviews, 2023, 502: 215618
Reviewed advancements in probes targeting the Golgi apparatus for cellular imaging.
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“Recent Progress in the Development of Small-Molecule Double-Locked Logic Gate Fluorescence Probes”
Chemical Communications, 2023, 59: 11017-11027
Discussed the evolution of logic gate-based fluorescence probes for biosensing.
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“Treatment Evaluation of Rheumatoid Arthritis by In Situ Fluorescence Imaging of the Golgi Cysteine”
Talanta, 2023, 270: 125532
Investigated the role of Golgi cysteine in rheumatoid arthritis treatment using fluorescence imaging.
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“Exploring Idiopathic Pulmonary Fibrosis Biomarker by Simultaneous Two-Photon Fluorescence Imaging of Cysteine and Peroxynitrite”
Analytical Chemistry, 2022, 94(32): 11272-11281
Utilized two-photon imaging to identify biomarkers in pulmonary fibrosis.
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“Simultaneous Fluorescence Imaging of Golgi O₂ and Golgi H₂O₂ in Mice with Hypertension”
Biosensors and Bioelectronics, 2022, 213: 114480
Monitored oxidative stress in hypertensive mice through Golgi-targeted imaging.
Conclusion:
Dr. Wang Hui is highly suitable for the Best Researcher Award based on:
- Deep scientific expertise in molecular probe development.
- Strong record of impactful research, patent filings, and national-level funding.
- Consistent output in top-tier international journals.
Although aspects like citation metrics, editorial roles, and industry collaborations could further strengthen the application, these are not critical omissions. Dr. Wang’s contributions to early disease diagnosis using fluorescence imaging are timely, innovative, and aligned with global research priorities in medical diagnostics.