Professor, University of Bari, Italy
Prof. Sisto Margherita is a distinguished Full Professor of Human Anatomy at the University of Bari, Italy, with a strong background in human and experimental morphology. Her research spans immunology, molecular biology, and autoimmune diseases, particularly focusing on Sjögren’s syndrome and fibrotic disorders. With an academic career dedicated to teaching and research, Prof. Sisto collaborates internationally with several prestigious institutions, contributing to advancements in autoimmune pathophysiology. Her work has made significant contributions to understanding the molecular mechanisms underlying chronic inflammatory diseases, inflammation, and immune responses.
Profile
Education
Prof. Sisto graduated cum laude in Biological Sciences from the University of Bari in 1997, followed by a Ph.D. in Human and Experimental Morphology in 1999. She also specialized in “Biology of Human and Animal Reproduction” and became board-certified as a Biologist in 1998. Throughout her academic journey, Prof. Sisto has demonstrated a dedication to advancing the fields of molecular immunology and human anatomy, shaping her impressive career in academia and research.
Experience
Prof. Sisto’s career spans several roles at the University of Bari, Italy, including researcher and adjunct professor. Since 2003, she has taught Human Anatomy across a variety of programs, such as Medicine, Nursing, and Biomedical Laboratory Techniques. She has supervised numerous graduate and postgraduate students and contributed significantly to Ph.D. programs in applied morphobiology and cellular sciences. Since 2019, Prof. Sisto has held the position of Full Professor of Human Anatomy, cementing her influence in academic leadership and education.
Awards and Honors
Prof. Sisto has received several accolades for her research. Notably, in 2011, she won the MD Honors Research Award with a $10,000 grant for her project on “The NF-kB Pathway as a Potential Target for Autoimmune Disease Therapy.” Additionally, she has been awarded multiple research grants, including funding from M.U.R.S.T and the Italian Ministry for Research and Higher Education. Her work is frequently recognized by scientific societies, and she is an active peer reviewer for several prestigious journals.
Research Focus
Prof. Sisto’s research primarily focuses on the molecular immunology of autoimmune diseases, particularly Sjögren’s syndrome. She investigates the role of autoantibodies in disease pathogenesis, explores immune regulation in autoimmunity, and studies inflammation’s impact on chronic diseases. Her work on macrophage and granulocyte activity, including their polarization and apoptosis, aims to uncover novel therapeutic strategies for autoimmune and fibrotic diseases. Prof. Sisto is at the forefront of research on emerging molecular therapies targeting inflammation and autoimmune disorders.
Publication Top Notes
- Epigenetic Modulations of Non-Coding RNAs: A Novel Therapeutic Perspective in Sjögren’s Syndrome 🧬
- Molecular Mechanism in Epithelial-Mesenchymal Transition (EMT) and Fibrosis 🔬
- Epigenetic Regulation of EMP/EMT-Dependent Fibrosis 🧬
- Targeting Interleukin-17 as a Novel Treatment Option for Fibrotic Diseases 💉
- Interleukin-23 Involved in Fibrotic Autoimmune Diseases: New Discoveries 🧫
- Immune and Non-Immune Inflammatory Cells Involved in Autoimmune Fibrosis: New Discoveries 🩺
- Towards a Unified Approach in Autoimmune Fibrotic Signalling Pathways 🔍
- Molecular Mechanisms Linking Inflammation to Autoimmunity in Sjögren’s Syndrome: Identification of New Targets 💡
- Diseases of the Salivary Glands-Part II 🦷
- The Expression of Follistatin-like 1 Protein Is Associated with the Activation of the EMT Program in Sjögren’s Syndrome 🧪