Nontobeko Mvubu | Medical Microbiology | Best Researcher Award

Dr. Nontobeko Mvubu | Medical Microbiology | Best Researcher Award

Senior Lecturer, University of KwaZulu-Natal, South Africa

Dr. Nontobeko Eunice Mvubu is a Senior Lecturer and Researcher at the University of KwaZulu-Natal (UKZN), specializing in Mycobacterium tuberculosis and Bioinformatics. She completed her PhD in Microbiology in 2016 and was promoted to Senior Lecturer in 2023. With over five years of teaching and research experience, she has supervised numerous students, including 11 Honours, 6 Masters, and 1 PhD. Dr. Mvubu has published 12 research articles in prestigious international journals and has been a reviewer for scientific publications for five years. Her commitment to research is demonstrated through national and international collaborations, alongside funding received for her projects. Dr. Mvubu’s expertise in microbiology, bioinformatics, and immunology, alongside her strong academic leadership, positions her as a key figure in the field of tuberculosis research.

Profile

Education

Dr. Mvubu completed her PhD in Microbiology at the University of KwaZulu-Natal (2013-2016). Before that, she earned a Master of Science in Microbiology, which was converted to a PhD. She also holds a BSc Honours in Microbiology (2010) from the same university. She began her academic journey with a Bachelor of Medical Science in Physiology from UKZN (2007-2009). Throughout her academic career, Dr. Mvubu has pursued various professional development courses, including a University Education Induction Programme, Supervising Research in Higher Education, and Bioinformatics Training at the University of the Western Cape, equipping her with the skills for higher education teaching and research.

Experience

Dr. Mvubu’s academic career spans roles from Lecturer (2017) to Senior Lecturer (2023) at the University of KwaZulu-Natal. Her teaching experience covers diverse subjects, including Genetics, Microbiology, Medical Microbiology, and Human Physiology, where she has coordinated and lectured several undergraduate and postgraduate courses. Her research and teaching roles extend to the supervision of students at various levels, including Honours, Masters, and PhD students. With a strong background in research, Dr. Mvubu has contributed to national and international research funding and has collaborated with various institutions. She has been involved in a range of high-level grants, including the National Research Foundation Thuthuka and South African Medical Research Council’s Self-Initiated Research Grants.

Awards and Honors

Dr. Mvubu has received recognition for her outstanding research and academic contributions, including being the principal investigator for the National Research Foundation’s Thuthuka Funding instrument (2018 and 2021). She has also played a co-investigator role in significant projects such as the Afrocentric Precision Approach to Control Health Epidemics (APACHE) in 2019. Her research has earned her publication in prominent journals like BMC Genomics and International Journal of Molecular Sciences. Through these contributions, she has gained recognition as a key researcher in her field. Dr. Mvubu’s academic and research achievements position her as a promising candidate for further research leadership and awards.

Research Focus

Dr. Mvubu’s research primarily focuses on the biology of Mycobacterium tuberculosis, with an emphasis on bioinformatics and molecular networks. She explores the role of lipid metabolism, immune response, and transcriptome regulation in tuberculosis infections. Her research has extended to studying the differential behavior of Mycobacterium tuberculosis strains, particularly how they affect cellular environments, immune responses, and gene regulation. She is also exploring the potential of medicinal plants and their bioactive compounds in regulating inflammasome pathways to combat tuberculosis. Her interdisciplinary approach, combining microbiology, bioinformatics, and immunology, aims to provide new insights into tuberculosis treatment and vaccine development.

Publication Top Notes

  • A review of documented antimicrobial and immunomodulatory properties of ethnomedicinal plants 🌿
  • Reclassification of Bacillus tropicus phage 🔬
  • Exploiting inflammasomes in tuberculosis therapy 🧬
  • Mycobacterium tuberculosis molecular networks 🦠
  • Protocol for RNA extraction from Mycobacterium tuberculosis 🔬
  • Differential lipid metabolism in tuberculosis strains 🧪
  • Exploring bioactive derivatives as inflammasome regulators 🌱
  • Neuroinflammation caused by tuberculosis in mice 🧠
  • Maternal immune activation and autism-like phenotype 👶
  • Lipid metabolism in Mycobacterium tuberculosis strains 🧬
  • Pulmonary epithelial cell infection by tuberculosis 🫁
  • Strain-specific immune response in Mycobacterium tuberculosis 🧫

Cyrille BIsseye | Infectious diseases | Best Researcher Award

Assoc. Prof. Dr. Cyrille BIsseye | Infectious diseases | Best Researcher Award

Senior Researcher, USTM, Gabon

Cyrille Bisseye, M.Sci., Ph.D., is an Associate Professor of Molecular Biology and Immunology at the University of Science and Technology of Masuku (USTM) in Franceville, Gabon. He is also the Head of the Laboratory of Molecular and Cellular Biology (LABMC) and the Agrobiology Research Unit (URAB). Dr. Bisseye’s academic and professional background is distinguished by a strong focus on infectious diseases, molecular biology, and immunology. With years of international research experience, including positions at the International Center for Medical Research in Franceville and Joseph KI-ZERBO University, Ouagadougou, he has contributed significantly to the field. His work spans various aspects of tropical diseases, with a particular emphasis on malaria, parasitology, and transfusion-related infections. Dr. Bisseye is also a dedicated educator, teaching and mentoring students in molecular biology, immunology, and parasitology.

Profile

Education  

Dr. Cyrille Bisseye earned his Bachelor’s in Biology of Organisms from Jean Monnet University, France, in 1995, followed by a Master’s in Biology of Organisms and Ecosystems in 1996. He further pursued a Master’s in Tropical Infectious Diseases from the Regional Doctoral School of Tropical Infectious Diseases, Central Africa (AUF), Gabon, in 1999. In 2011, he completed his Ph.D. in Immunology and Parasitology at Joseph KI-ZERBO University, Ouagadougou, Burkina Faso. His thesis focused on “Humoral and Cellular Immune Responses Against Plasmodium falciparum Vaccine Candidates’ Antigens in a Seasonally Transmitted Malaria-Endemic Area.” This comprehensive educational foundation equipped Dr. Bisseye with a deep understanding of molecular biology, immunology, parasitology, and their application to tropical infectious diseases. His academic journey spans multiple continents and institutions, laying the groundwork for his current research and teaching expertise in the field.

Experience 

Dr. Cyrille Bisseye has extensive experience in molecular biology and immunology, particularly in the context of infectious diseases. From January 2018, he has served as the Head of the Laboratory of Molecular and Cellular Biology (LABMC) at USTM, Franceville, Gabon. Previously, from May 2012 to December 2017, he worked as a researcher in molecular biology and immunology at the same institution. Dr. Bisseye also held several key research positions at prominent institutions, including the Pietro Annigoni Biomolecular Research Center, Burkina Faso, and the Medical Research Council (MRC), UK, where he contributed to malaria immunology, human genetics, and tropical diseases. His training and work experience in countries such as Gabon, Burkina Faso, and the UK have provided him with invaluable insights into the molecular mechanisms of infectious diseases, including malaria and hepatitis. He has also worked on a range of diagnostic techniques, from PCR to flow cytometry.

Research Focus 

Dr. Cyrille Bisseye’s research focuses primarily on tropical infectious diseases, including malaria, viral hepatitis, tuberculosis, HIV, and other transfusion-transmissible infections prevalent in sub-Saharan Africa. He is particularly interested in genetic factors associated with susceptibility to or protection against these diseases, with significant work on Plasmodium falciparum malaria. His research also delves into the epidemiology and molecular diagnostics of various pathogens, aiming to improve public health outcomes in Africa. One of his key research themes is transfusion safety and the prevalence of blood-borne infections, especially in the context of first-time blood donors. Dr. Bisseye’s research extends to the molecular biology of parasites and host immune responses, including humoral and cellular immunity. He is actively involved in systemic reviews and meta-analyses aimed at understanding the seroprevalence of diseases such as hepatitis B in sub-Saharan Africa. His work contributes to the development of diagnostic tools and vaccine candidates for these critical diseases.

Publication Top Notes

  • “Seroprevalence of Viral Hepatitis B and Occult Hepatitis B Among Blood Donors in Africa: A Systematic Review and Meta-Analysis” 📑
  • “C-reactive protein and high-sensitivity C-reactive protein levels in asymptomatic intestinal parasite carriers from urban and rural areas of Gabon” 🔬
  • “Prevalence of cardiometabolic risk factors according to urbanization level, gender, and age, in apparently healthy adults living in Gabon” 🏥
  • “Determinants of low birth weight in Franceville, Southeast Gabon” 🍼
  • “Microfilariae Prevalence and its Association with Anemia Among First-time Blood Donors in Lambaréné, Gabon” 🩸
  • “Epidemiology of community origin of major multidrug-resistant ESKAPE uropathogens in a paediatric population in South-East Gabon” 💉
  • “Natural Non-Polio-Enteroviruses Detected in Captive Mandrills (Mandrillus sphinx) and Chimpanzees (Pan troglodytes troglodytes) Housed in a Primate Center in Franceville, Gabon” 🦧
  • “Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon” 🦟
  • “Prevalence and Loa loa Filariasis Risk Factors: Case of Koula-Moutou and Surrounding Departments, in Central-Eastern Gabon” 🌍
  • “A comparative analysis of blood-borne infections among sickle cell anemia patients and first-time donors in Gabon” 🩸