Hui Wang | Molecular Fluorescence Probes | Best Researcher Award

Assoc. Prof. Dr. Hui Wang | Molecular Fluorescence Probes | Best Researcher Award

Associate professor, doctoral supervisor, Shandong Normal University, China

Dr. Wang Hui is an Associate Professor and doctoral supervisor at Shandong Normal University, specializing in molecular fluorescence probes for real-time in vivo imaging. Her research focuses on developing probes for detecting reactive oxygen species (ROS) and proteins in live organisms, aiming to enhance early diagnosis and understanding of diseases such as atherosclerosis, rheumatoid arthritis, and idiopathic pulmonary fibrosis. Dr. Wang has authored over 30 peer-reviewed articles in high-impact journals like Angewandte Chemie International Edition and Analytical Chemistry. She has also filed multiple patents related to her probe technologies. Her work has been recognized by the National Natural Science Foundation of China and the Shandong Provincial Natural Science Foundation. Dr. Wang is a member of the Chinese Chemical Society and collaborates with the Institute of Oceanology, Chinese Academy of Sciences, on projects related to marine pollution.

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Education

Dr. Wang Hui completed her undergraduate studies in Physics at Shandong Normal University from 2013 to 2017. She then pursued a Ph.D. in Chemistry at Nankai University, graduating in 2022. Her doctoral research focused on the development of molecular fluorescence probes for bioimaging applications. Throughout her academic journey, Dr. Wang has been involved in various research projects, including those funded by the National Natural Science Foundation of China and the Shandong Provincial Natural Science Foundation. Her educational background has provided her with a strong foundation in both theoretical and practical aspects of molecular chemistry and bioimaging techniques.

Experience

Dr. Wang Hui has extensive experience in the field of molecular fluorescence probes and bioimaging. Since joining Shandong Normal University, she has led several research projects aimed at developing innovative probes for detecting ROS and proteins in live organisms. Her work has led to the creation of novel probes such as the C-HBrO-GGT and GolgiROS, which have been instrumental in studying diseases like atherosclerosis and hypertension. Dr. Wang has also been involved in collaborations with institutions like the Institute of Oceanology, Chinese Academy of Sciences, focusing on environmental applications of fluorescence probes. Her contributions have been recognized through numerous publications in high-impact journals and several patents.

Research Focus

Dr. Wang Hui’s research focuses on the development of molecular fluorescence probes for specific imaging of biomolecules. By combining these probes with fluorescence imaging technology, her work aims to achieve early warning and diagnosis of major diseases such as atherosclerosis, rheumatoid arthritis, and idiopathic pulmonary fibrosis. Her innovative approaches include the development of dual-mode fluorescent probes and two-photon fluorescence imaging techniques to detect bioactive molecules like ROS and proteins in the lesion sites of live mice. These advancements have the potential to significantly enhance early disease diagnosis and drug discovery, providing fundamental tools for real-time organelle-level redox research.

Publication Top Notes

  1. “Prediction of Early Atherosclerotic Plaques Using a Sequence‐Activated Fluorescence Probe for the Simultaneous Detection of γ‐Glutamyl Transpeptidase and Hypobromous Acid”
    Angewandte Chemie International Edition, 2023, 136(1): e202315861
    Developed a dual-activated probe for early detection of atherosclerotic plaques.

  2. “Fluorescence Probes for Sensing and Imaging within Golgi Apparatus”
    Coordination Chemistry Reviews, 2023, 502: 215618
    Reviewed advancements in probes targeting the Golgi apparatus for cellular imaging.

  3. “Recent Progress in the Development of Small-Molecule Double-Locked Logic Gate Fluorescence Probes”
    Chemical Communications, 2023, 59: 11017-11027
    Discussed the evolution of logic gate-based fluorescence probes for biosensing.

  4. “Treatment Evaluation of Rheumatoid Arthritis by In Situ Fluorescence Imaging of the Golgi Cysteine”
    Talanta, 2023, 270: 125532
    Investigated the role of Golgi cysteine in rheumatoid arthritis treatment using fluorescence imaging.

  5. “Exploring Idiopathic Pulmonary Fibrosis Biomarker by Simultaneous Two-Photon Fluorescence Imaging of Cysteine and Peroxynitrite”
    Analytical Chemistry, 2022, 94(32): 11272-11281
    Utilized two-photon imaging to identify biomarkers in pulmonary fibrosis.

  6. “Simultaneous Fluorescence Imaging of Golgi O₂ and Golgi H₂O₂ in Mice with Hypertension”
    Biosensors and Bioelectronics, 2022, 213: 114480
    Monitored oxidative stress in hypertensive mice through Golgi-targeted imaging.

Conclusion:

Dr. Wang Hui is highly suitable for the Best Researcher Award based on:

  • Deep scientific expertise in molecular probe development.
  • Strong record of impactful research, patent filings, and national-level funding.
  • Consistent output in top-tier international journals.

Although aspects like citation metrics, editorial roles, and industry collaborations could further strengthen the application, these are not critical omissions. Dr. Wang’s contributions to early disease diagnosis using fluorescence imaging are timely, innovative, and aligned with global research priorities in medical diagnostics.

 

 

Maisa Araujo | Entomologist | Best Researcher Award

Dr. Maisa Araujo | Entomologist | Best Researcher Award

Researcher, Fiocruz Rondônia, Brazil

Maisa da Silva Araujo is a researcher and professor specializing in parasitology, entomology, and tropical diseases. With a strong background in malaria vector biology and molecular biology, she is dedicated to advancing the understanding of parasite-vector interactions. Currently, she is an Associate Researcher at the Translational and Clinical Research Lab and a Professor at the University of Rondônia. She has contributed to the development of a unique mosquito colony used for malaria research and is working on liver-stage drug assays for Plasmodium vivax. As a Principal Investigator and co-investigator on multiple funded projects, her leadership in collaborative research has led to significant advancements in vector control and malaria transmission-blocking strategies. Araujo’s expertise and innovation continue to impact the global fight against malaria, bringing new insights into vector behavior, microbiota, and drug screening.

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Education

Maisa da Silva Araujo began her academic journey with a Bachelor’s in Biology from the Faculty of Education of Porto Velho (2004). She then completed her Master’s (2008) and PhD (2013) in Experimental Biology at the University of Rondônia, specializing in Malaria and Molecular Biology. Her academic path continued with postdoctoral research in Molecular Biology and Entomology at Brandeis University, USA (2017). Throughout her studies, Araujo focused on tropical disease vectors, particularly Anopheles darlingi, a primary malaria vector. This strong academic foundation laid the groundwork for her expertise in molecular biology, vector biology, parasitology, and the development of innovative platforms for mosquito colonies used in malaria research. Her education reflects a dedication to understanding the molecular dynamics of disease transmission, providing a crucial framework for her ongoing research endeavors.

Experience

Maisa Araujo has extensive experience in malaria research, vector biology, and molecular parasitology. She has led and contributed to numerous research projects on malaria transmission, vector control, and drug discovery. As a postdoctoral researcher at Brandeis University and FIOCRUZ-Rondônia, she developed innovative techniques for maintaining laboratory colonies of Anopheles darlingi and other malaria vectors, a crucial step in studying parasite-vector interactions. She is the Principal Investigator for multiple projects focused on transmission-blocking drugs and insecticide resistance in malaria vectors. Araujo also played a significant role in creating a platform for the evaluation of new compounds targeting the liver stages of Plasmodium vivax. Her expertise in managing complex projects and research teams, as well as her experience with international collaborations, has solidified her as a leading figure in the field of tropical disease research. Araujo’s leadership continues to shape the direction of malaria research in Brazil and globally.

Awards and Honors

Maisa da Silva Araujo has received numerous accolades for her pioneering work in malaria research and entomology. Notably, she was awarded the Young Trajectories in Malariology Award by the Instituto Oswaldo Cruz, Fiocruz, Brazil, in 2022. This honor recognized her significant contributions to advancing the understanding of malaria transmission and vector control strategies. Her research has also been supported by various prestigious grants, including funding from organizations like GlaxoSmithKline (GSK), the Bill & Melinda Gates Foundation, and the Medicines for Malaria Venture (MMV). Araujo’s work in establishing laboratory colonies of malaria vectors and her contributions to drug screening platforms have earned her international recognition. Her ability to bridge the gap between research and practical applications in vector control and malaria prevention continues to earn her accolades from both national and international scientific communities.

Research Focus

Maisa Araujo’s research primarily focuses on understanding malaria transmission dynamics, with an emphasis on vector biology, parasite-vector interactions, and drug discovery. She has made significant advancements in establishing laboratory colonies of Anopheles darlingi and Anopheles deaneorum, crucial malaria vectors in Brazil, facilitating the study of their interactions with Plasmodium parasites. Araujo is also working on developing new platforms for testing antimalarial drugs targeting the liver stage of Plasmodium vivax. Her work in insecticide resistance surveillance and transmission-blocking strategies plays a critical role in malaria control efforts. By investigating the microbiota of mosquito vectors and their role in parasite transmission, Araujo’s research offers novel insights into vector behavior and ecology. She also focuses on screening new compounds for their potential to reduce malaria transmission, thereby contributing to the global goal of eliminating malaria. Her work has both scientific and practical implications for malaria control worldwide.

Publication Top Notes

  1. “Case Report: Plasmodium vivax Sporozoite Melanization in the Midgut and Salivary Gland of the Malaria Vector Anopheles darlingi” 🦟🔬

  2. “Transmission-reducing and -enhancing monoclonal antibodies against Plasmodium vivax gamete surface protein Pvs48/45” 💉🦠

  3. “Transmission-blocking activity of antimalarials for Plasmodium vivax malaria in Anopheles darlingi” 💊🦟

  4. “Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi” 🦠🌿

  5. “Bacterial Microbiota from Lab-Reared and Field-Captured Anopheles darlingi Midgut and Salivary Gland” 🦠🔬